Skin Types
Dry, Normal, Oily, Combination.
What it does
This cutting-edge serum targets signs of aging and increases elasticity using ProPhagy®, a patented concentrate derived from the cherry tomato that is 2.5X more potent than vitamin C. Developed using Nobel Prize-winning autophagy research, this powerful active targets fine lines and boosts skin’s glow by diminishing intracellular damage. Together with Roxisomes® from the plant Arabidopsis Thaliana and Ultrasomes®, ProPhagy® supports skin’s natural recovery process without causing dryness or irritation. This innovative formula also includes diglucosyl gallic acid to improve skin’s texture, peptide SYN®-AKE to help reduce the appearance of wrinkles and laughter lines, as well as pterostilbene-rich European blueberry extract to repair existing sun damage and combat free radicals.
How to use
Apply to face each morning and evening after cleansing the skin and before moisturizer. Avoid direct contact with eyes and lips. Store in a cool, dark place.
Product texture
Pale yellow light gel
PROPHAGY®
Cherry Tomato Extract
Glow Boosting
Autophagy is a natural, regulated mechanism in cell to cleanse waste and recycle old parts¹. It’s a novel mechanism and pioneering technology used in skincare for anti-aging. The 2016 Nobel Prize for Physiology or Medicine was awarded to Dr. Yoshinori Ohsumi for his discoveries of the underlying the mechanism of autophagy².
Prophagy® is the first autophagy inducer discovered from natural source included in a skincare product. 2.5 times as potent as Vitamin C in melanocytes at the same concentration, Prophagy® helps to restore skin radiance by removing excessive melanin. Additionally, Prophagy® is scientifically proven to decrease skin chronic inflammation, which is one main factor causes wrinkles and fine lines.
Blueberry
Antioxidant
Inhibits the oxidation process in melanogenesis.
Arabidopsis
Anti-photoaging
Identifies DNA damage and initiates the natural cellular repair process.
Diglucosyl Gallic Acid
Enhances Glow
Alleviates inflammation and evens skin tone.
Cork Oak Bark
Firming & Lifting
Forms a microcrystalline network that binds to the skin surface and progressively tighten the skin.
Hyaluronic Acid
Plumping
Helps skin to hold moisture and promotes collagen production.
Ergothioneine
Super Antioxidant
Resists photoaging, brightens skin and protects cells from UV-induced ROS.
Learn More About Autophagy
Step of Autophagy
Transport to lysosomes, degradation, and utilization of degradation products.
Reference
1. Hansen, Malene, David C. Rubinsztein, and David W. Walker. "Autophagy as a promoter of longevity: insights from model organisms." Nature Review Mol Cell Biol 19 (2018): 579-93.
2. The Nobel Prize in Physiology or Medicine (2016). Discoveries of Mechanisms for Autophagy. Retrieved 3 Oct 2016
Autophagy Detection by Fluorescence Microscopy
Cells treated with Prophagy® or rapamycin (positive control) were incubated with Green Detection Reagent and Nuclear Stain.
Standard FITC filter set was used for imaging the autophagic signal. DAPI filter set was used for the imaging of nuclear. Images were analyzed by fluorescence microscopy.
Full ingredient list
Aqua (Water), Glycerin, Propanediol, Dipropylene Glycol, Butylene Glycol, Ethoxydiglycol, 1,2-Hexanediol, Solanum Lycopersicum (Tomato) Fruit Extract, Micrococcus Lysate, Arabidopsis Thaliana Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Diglucosyl Gallic Acid, Vaccinium Angustifolium (Blueberry) Fruit Extract, Quercus Suber Bark Extract, Ergothioneine, Hyaluronic Acid, Tocopherol, Tricholoma Matsutake Extract, Biosaccharide Gum-1, Lecithin, Hydroxyacetophenone, Pentylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Carbomer, Ethylhexylglycerin, Alcohol Denat, Sodium Hydroxide, Sodium Phytate.
Packed with actives proven to work better than harsh chemicals, our 9-free standard within Clean I.Q.™ system leaves out suspicious synthetics and toxins. If an ingredient doesn’t safely serve your skin, we skip it.
9- Free Clean Standard
based on scientific judgment
No SLS/SLES
An inexpensive cleanser that strips lipids from the skin, damages the natural skin barrier and causes irritation.
We use mild surfactants made of amino acids or plant-derived glucoside.
No Parabens
Traditional preservatives that can enter the body through the skin, and disrupt a healthy endocrine system.
We use advanced preservatives that pose a low risk of skin irritation.
No Propylene Glycol
Commonly found in fragrance and nail polish, these chemicals have been linked to hormone disruption.
We use 1,3-propanediol made from corn sugar.
No Synthetic Dyes
Derived from petrochemicals, dyes may cause allergic reactions, skin sensitization, and eye irritation.
Free of any artificial dyes, the colors of our formulas come only from ingredients themselves.
No Hydroquinone
This controversial and antiquated lightening agent is toxic to melanocytes and may cause skin discoloration.
We use award-winning, next-generation ingredients that are both potent and safe for use on all skin tones.
No Mineral Oil
A liquid commonly derived from petroleum that may contain polycyclic aromatic hydro-carbons, cancer-causing chemicals found in crude oil and its by-products.
We use naturally sourced or ECOCert®-certified oils.
No Formaldehyde Releasers
These traditional preservatives can be absorbed through the skin, leading to allergic reactions and hormone disruption.
We use advanced preservatives derived from natural sources that pose a low risk of skin irritation.
No Phthalates
Commonly found in fragrance and nail polish, these chemicals have been linked to hormone disruption.
Our formulas are completely void of dibutyl phthalate (DBP), di-2-ethylhexylphthalate (DEHP), and diethyl phthalate DEP.
No Fragrances
Both natural and synthetic fragrances can contain hundreds of undisclosed chemicals, many of which are considered allergens.
Our formulas’ subtle scents are the result of our ingredients themselves. We never add any potentially irritating perfumes.
Aqua (Water), Glycerin, Propanediol, Dipropylene Glycol, Butylene Glycol, Ethoxydiglycol, 1,2-Hexanediol, Solanum Lycopersicum (Tomato) Fruit Extract, Micrococcus Lysate, Arabidopsis Thaliana Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Diglucosyl Gallic Acid, Vaccinium Angustifolium (Blueberry) Fruit Extract, Quercus Suber Bark Extract, Ergothioneine, Hyaluronic Acid, Tocopherol, Tricholoma Matsutake Extract, Biosaccharide Gum-1, Lecithin, Hydroxyacetophenone, Pentylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Caprylyl Glycol, Carbomer, Ethylhexylglycerin, Alcohol Denat, Sodium Hydroxide, Sodium Phytate.